Obstetrics & gynaecology

No link found for exposure to epidural labor analgesia and autism

(HealthDay)—Exposure to epidural labor analgesia (ELA) is not associated with offspring risk for autism spectrum disorder (ASD), according to a study published online April 19 in JAMA Pediatrics.

Elizabeth Wall-Wieler, Ph.D., from the University of Manitoba in Winnipeg, Canada, and colleagues conducted a longitudinal cohort study of vaginal deliveries of singleton live infants born from 2005 to 2016 to examine the correlation between ELA and offspring risk for ASD. Data were included for 123,175 offspring, of whom 38.2 percent were exposed to ELA.

The researchers found that 2.1 percent of those exposed to ELA and 1.7 percent of unexposed offspring were diagnosed with ASD during the follow-up period (hazard ratio, 1.25; 95 percent confidence interval, 1.15 to 1.36). ELA was not associated with an offspring risk for ASD after adjustment for maternal sociodemographic, prepregnancy, pregnancy, and perinatal covariates (inverse probability of treatment-weighted hazard ratio, 1.08; 95 percent confidence interval, 0.97 to 1.20). ELA was not associated with ASD in the within-siblings design adjusting for baseline covariates (inverse probability of treatment-weighted hazard ratio, 0.97; 95 percent confidence interval, 0.78 to 1.22).

“This finding is of clinical importance in the context of pregnant women and their obstetric and anesthesia care professionals who are considering ELA during labor,” the authors write.

One author disclosed financial ties to the pharmaceutical industry.

Hypertensive disorders of pregnancy tied to child neurodevelopment

Copyright © 2021 HealthDay. All rights reserved.

No link found for exposure to epidural labor analgesia and autism (2021, April 20)
retrieved 20 April 2021
from https://medicalxpress.com/news/2021-04-link-exposure-epidural-labor-analgesia.html

This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no
part may be reproduced without the written permission. The content is provided for information purposes only.

Source link

Leave a Reply

Your email address will not be published. Required fields are marked *

Back to top button

Ad Block Detected

Welcome to Mediexpose, Please support our journalism by allowing ads. With support from readers like you, we can continue to deliver the best. You can support us free by simply allowing ads.